BDBM21281 (11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphthalen-1-ylcarbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4(12),5,7-tetraene::(2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl)methanone monomethanesulfonat::CHEMBL188::WIN 55,212-2::WIN 55212-2::WIN-55212::WIN55212-2
SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23
InChI Key InChIKey=HQVHOQAKMCMIIM-HXUWFJFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 112 hits for monomerid = 21281
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [131I]-(R)-8More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to human CB1 receptor by filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to displace [3H]CP-55,940 from CB1 receptor of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Agonist activity at CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity towards cloned human Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity of compound was determined against to human cannabinoid receptor 1 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB1 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Compound was evaluated for its binding affinity against Cannabinoid receptor 1 in Guinea pig ileum (GPI) using [3H]CP-55940 ligandMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity to CB1 cannabinoid receptor using [3H]WIN-55212-2 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6.06nMAssay Description:Binding affinity to human cannabinoid CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.06nMAssay Description:Displacement of [3H]CP-55940 from cannabinoid CB1 receptor in rat brain cortical membraneMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nM ΔG°: -11.3kcal/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.90nMAssay Description:Binding affinity for cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-WIN55212-2 from CB1R in rat brain membranes incubated for 60 mins by radioligand competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]CP-55,940 from human recombinant CB1 receptor expressed in CHO cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with wild type Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 12.4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cell membranes incubated for 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB1 receptor expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]CP-55,940 from human CB1 receptor expressed in CHO cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13.3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13.3nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
Affinity DataKi: 13.3nM ΔG°: -10.9kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]CP-55,940 from Sprague-Dawley rat brain CB1 receptor by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with F3.25 (190)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 15.6nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in CHO cell membranes after 1 hr by beta-counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [3H]SR-141,716AMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair